side effect of justicia carnea side effect of justicia carnea

Justicia carnea is affects Fertility according to a researched article published on ResearchgateJusticia carnea was found to lower sperm count Male Wistar Albino ratsthe effect of this herb on female fertility is not yet known. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Inter J Pharm Sci Res. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. Justicia carnea is amedicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Aim. Hence, Justicia carnea can be used to strengthen the immune system. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. View abstract. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. The absorbance was read at 412nm against the reagent blank. Phytochemical profile, antioxidant, -amylase inhibition, binding Antianaemic potentials of some plant extracts on phenyl hydrazineinduced anemia in rabbits. Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). Canadian J Appl Sci. You can add milk or honey for taste before drinking. In traditional medicine, justicia carnea is used in treating hepatitis. Philadelphia: WB. Haematological and biochemical studies on Justicia carnea - PubMed Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America. 16. J Acute Disease. Not sure which Justicia to pick?Compare All Justicia. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. Organic extract of Justicia pectoralis Jacq. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. He has B.Sc.,and M.Sc. . The result of hematology indices is presented in Table3. Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. The changing faces of glutathione, a cellular protagonist. How long does it take for Aju mbaise to work. Safety assessment of oral administration of ethanol extract of, $$ \mathrm{Total}\ \mathrm{protein}\kern0.5em =\kern0.5em \frac{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{sample}}{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{standard}}\kern0.5em \times \kern0.5em \mathrm{Concentration}\ \mathrm{of}\ \mathrm{standard} $$, $$ \mathrm{Catalase}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}\right)=\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{SOD}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}/\mathrm{mg}\ \mathrm{protein}\right)\kern0.5em =\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{Concentration}\kern0.5em \mathrm{of}\kern0.5em \mathrm{reduced}\kern0.5em \mathrm{GSH}\kern0.5em =\kern0.5em \frac{\left(\Delta \mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\left(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}\right)} $$, $$ \mathrm{Malondialdehyde}\kern0.5em =\kern0.5em \frac{\left(\mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\Big(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, https://doi.org/10.1186/s40816-020-00234-4, https://doi.org/10.1016/j.jep.2015.06.005, https://doi.org/10.1016/j.joad.2015.08.006, https://doi.org/10.1016/j.jep.2005.06.013, https://doi.org/10.3109/08860220903367585, https://doi.org/10.1590/S0102-695X2011005000196, https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867, https://doi.org/10.35841/biomedicalresearch.30-18-666, https://doi.org/10.1016/j.jep.2007.02.011, https://doi.org/10.1186/s40816-019-0104-4, https://doi.org/10.1016/j.fitote.2008.02.005, https://doi.org/10.1016/j.jada.2008.06.430, https://doi.org/10.1016/j.biocel.2006.07.001, https://doi.org/10.1186/s12906-015-0760-y, http://creativecommons.org/licenses/by/4.0/. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Note this is the default cart. They also maintain our skin tone and texture, and help in reproductive functions. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. 4. Lorke D. A new approach to practical acute toxicity testing. J Ethnopharmacol. They protect our cells from the harmful effects of reactive oxygen species. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. Turn off the heat and then soak the leaves into the pot. WBC reduced in rats treated with doses of J. carnea with significant decrease (p<0.05) in rats that received 50, 100 and 1200mg/kg body weight. Justicia pectoralis seems to have antibacterial and anti-inflammatory effects. Rich, well-drained soil retaining ample moisture is the perfect home for Brazilian plume flowers. J Ethnopharmacol 1999;64(3):265-270. They range in colors such as red, orange, mauve, magenta, apricot, and pink. The fresh leaves were thoroughly washed under running tap, air dried under shade, pulverized and extracted with ethanol. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. View abstract. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. Ewe eje as it is fondly called by the Westerners in Nigeria is a plant known for its blood boosting abilities. 1978;90:819. This is in agreement with study of Anthonia et al., [21] who obtained LD50 above 5000mg/kg for aqueous extracts of J. carnea leaf. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. The package will tell you exactly how, when, and how much feed to use. The weight of organs (liver and kidney) reduced steadily in a concentration dependent manner. Haematological and biochemical studies on Justicia carnea leaves extract in phenylhydrazine induced-anemia in albino rats. Plantcaretoday.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com, how to get rid of leaf eating caterpillar. Aim. Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. 1978;52:30210. The red coloration of the decoction made people think that the plant must contain blood boosting compounds. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. Aside boosting blood production in normal persons, justicia carnea leaves also reverses anemic conditions. PubMed Excitedly, scientific studies have supported the traditional claims. Consumption of medicinal plants without scrutinizing its efficacy and safety can result in unexpected toxic effects resulting in physiology changes of different organs in the body. Deleting this collection CANNOT be undone. One of the oldest known plant is the fig tree. Author ESA managed the literature searches and wrote the first draft of the manuscript with the assistant of FOA. Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes. The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. Washington, DC: The National Academies Press; 1997. https://doi.org/10.17226/4988. what are the pros and cons of testosterone replacement therapy? Cookies, This site is protected by reCAPTCHA and the Google, Justicia scheidweileri (Purple Shrimp Plant), Justicia americana (American Water-Willow), Want Garden Inspiration? While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. Colorimetric assay of catalase. Nunes TRS, Cordeiro MF, Beserra FG, et al. Part shade is the ideal growing condition for Brazilian plumes. PubMed Rats were further observed for extended hours of 48h to see if mortality would occur. Keep in mind that natural products are not always necessarily safe and dosages can be important. All authors read and approved the final draft of the manuscript. The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. Fitoterapia. Acute and sub-acute toxicity studies of aqueous and methanol extracts of Nelsonia campestris in rats. No. As for light exposure, keep the plant away from the full sun. 2013;1:38898. 2005 - 2023 WebMD LLC, an Internet Brands company. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience 2011;5(9):48992 https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867. Accept Proximate analysis of the aqueous extract of J. carnea leaves showed that it contains appreciable amounts of 53.07 0.07% carbohydrate, 9.26 0.02% ash, and 26.71 0.02% . Onyeabo C, Achi NK, Ekeleme-Egedigwe CA, Ebere CU, Okoro CK. There is however little publications available on the pharmacological properties of the herbal plant. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. The gradual decrease in the weight of organs following short-term exposure of J. carnea leaf ethanol extract may be attributed to adaptive response of the organs arising from daily dosage of the extract or its metabolites within their body. 2005;102(2):197201. https://doi.org/10.1186/s40816-020-00234-4, DOI: https://doi.org/10.1186/s40816-020-00234-4. J Afr Ass Physiol Sci. Rats in the 3 different groups received 10, 100 and 1000mg/kg body weight of JCEE orally using oral gavage. View abstract. Authors KOK and ESA performed the statistical analysis and managed the analyses of study. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. However, coadministration of both extracts exerts a synergistic effecton the . The leaves of Justicia carnea contains powerful antioxidant activities and phytochemical components that help reduce oxidative stress, and reduce the risk of development of cancer. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Ewe eje is an age-old herb medically proven to act as a blood tonic which can be attributed to its nutritional composition. Watering depends on humidity and temperature. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. Onoagbe IO, Attah V, Luther MM, Esekheigbe A. Hypoglycemic and anti-diabetic effects of Morinda lucida and Tetracera alnifora in normal and streptozotocin-induced diabetic rats. The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. At the end of the 14th day of administration, the rats were allowed to fast overnight and sacrificed the following morning by anesthetizing each rat in a closed chamber containing drops of chloroform. A cup of ewe eje extract in the morning will provide you with energy needed to pull through the days activities. 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. View abstract. Studies on the Phytochemical and Nutritional Composition of Aqueous Leaf Extract of Justicia Carnea and its Effect on Some Biochemical Parameters in Anaemic Rats. 2003;84:99104. In this report, MCV, MCH and MCHC in treated group were not altered compared to the control. Biomed Res. Ogwu obara is commonly used in making porridge yam, and soups. For some, the boiling method is preferred while for others, soaking in hot water is more convenient. The aqueous leaf extract of ewe eje has demonstrated hypoglycaemic and antidiabetic properties; and thus, can be said to assist with blood sugar levels reduction. Cover and leave for about fifteen minutes. The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. Histopathological examinations of sections of the liver collected from the 4 One of the symptoms of diabetes is elevated blood glucose level. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. As a consequence, depletion of reduced glutathione (GSH) either by removal from the cell or oxidation to GSSG could eventually lead to mild oxidative stress in cells and tissues [33, 34]. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . Studies have shown that ewe eje isnt capable of causing damage to the liver. They should be watered regularly (once per week), but not overwatered. Yes my readers. W Afr J Biol Sci. When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. Safety assessment of oral administration of ethanol extract of Justicia Another plant with this benefit is fertility tree. II. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Although the antidepressant activity of justicia carnea has not been studied, and so may be hard to prove its efficacy scientifically, the leaves of justicia carnea have been used in traditional medicine to treat depression and anxiety disorder. This amazing, Coriander seeds as well as the leaves are widely used as spices in flavoring foods and drinks, and, Cashew leaves: health benefits and side effects of Anacardium occidentale, Fig leaves tea: Amazing benefits and best recipes, Negro pepper: 12 health benefits of uda seed and side effects. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. View abstract. Joseph, H., Gleye, J., Moulis, C., Fouraste, I., and Stanislas, E. O-Methoxylated C-glycosylflavones from Justicia pectoralis. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. It can be used to manage diabetes consition properly. They are also needed in strong bone formation, and in cellular and neuronal functions. J Ethnopharmacol. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. Different drugs are used but many depend mainly on plants and herbal products for its treatment. Pinch Justicia carnea plants back after theyve flowered. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere.